This is a minor inconvenience, as I can find a workaround when this happens. BUT, when I'm working with Sketcbook pro with my Artist Display 22E pro, the pressure sensitivity will stop working temporarily when I use the mouse on the other monitor (Instances such as using the web for photo references or just checking email and so forth). I know I can technically switch the display monitor with the Express key, but I only do that for workflow operations, and not general productivity. The workaround I've found is that I either expand or un-expand the window in my Artist display, and/or switch tools.  I've uninstalled and downloaded the latest drivers and other standard diagnostics, and it's still happening.